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Breast Gastrointestinal Genitourinary Gynecologic Hematology Lung Melanoma Solid Tumor

Phase

III II I

Molecule*

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Antibody drug conjugate (RG6109) Antibody drug conjugate (RG6148) Anti-MUC16 TDC (RG7882) Atezolizumab (anti-PDL1 MAb) (RG7446) BET inhibitor (TEN-010, RG6146) Bevacizumab (anti-VEGF MAb) CD20 x CD3 (RG6026) Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) ChK1 inhibitor (GDC-0575, RG7741) Cibisatamab (CEA x CD3) (RG7802) Cobimetinib (MEK inhibitor) (RG7421) Codrituzumab (anti–glypican 3 MAb) (CHU, RG7686) Emactuzumab (anti–CSF-1R MAb) (RG7155) Entrectinib (ROS1/TRK inhibitor) (RXDX-101, RG6268) FAP-4-1BBL FP (RG7827) FAP-DR5 biMAb (RG7386) FAP-IL2v FP (RG7461) Fixed dose combination SC pertuzumab + trastuzumab (anti-HER2 MAb) (RG6264) Glypican-3 x CD3 (CHU) HER2 x CD3 (RG6194) Idasanutlin (MDM2 antagonist) (RG7388) Individualized NeoAntigen Specific Immunotherapy (iNeST) (RG6180) Ipatasertib (AKT inhibitor) (GDC-0068, RG7440) Monoclonal antibody (RG6123) Monoclonal antibody (RG6160) Mosunetuzumab (CD20 x CD3) (RG7828) Obinutuzumab Pan-RAF inhibitor (RG6185) PD-1 x TIM3 (RG7769) PI3K inhibitor (GDC-0077, RG6114) PI3K inhibitor (RG6114) Polatuzumab vedotin (anti-CD79b ADC) (RG7596) Raf/MEK dual inhibitor (CHU) Selective estrogen receptor degrader (SERD[3]) (GDC-9545, RG6171) Selicrelumab (CD40 MAb) (RG7876) Taselisib (PI3K inhibitor) (GDC-0032, RG7604) Tiragolumab (anti-TIGIT MAb) (RG6058) Vanucizumab (ANG2-VEGF biMAb) (RG7221) Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601)

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Tumor Type: Breast, Gastrointestinal, Genitourinary, Gynecologic, Hematology, Lung, Melanoma, Solid Tumor

Phase: PHASE II

Region:

Molecule: Polatuzumab vedotin (anti-CD79b ADC) (RG7596)

For more information about recruiting clinical trials, please call the Trial Information Support Line for US Clinical Trial information at 888-662-6728 or visit ClinicalTrials.gov.
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Tumor Type Phase Molecule* Location Study Contact
Tumor
Type
Phase Molecule* Location
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab AZ NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab AZ
NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab FL NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab FL
NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab KS NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab KS
NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab TX NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Hematology II, I Mosunetuzumab (CD20 x CD3) (RG7828), Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab TX
NCT03677141—A Phase Ib/II Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Participants With B-Cell Non-Hodgkin Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab AU NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab AU
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab CA NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab CA
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab CA NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab CA
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab FL NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab FL
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab FR NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab FR
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab GB NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab GB
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab HU NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab HU
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab IT NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab IT
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab KR NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab KR
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab NA NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab NA
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab NY NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab NY
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Tumor
Type
Phase Molecule* Location
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab TR NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
Hematology II, I Obinutuzumab, Polatuzumab vedotin (anti-CD79b ADC) (RG7596), Rituximab TR
NCT02257567—A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma
1 of 16 clinical trials
1-4 of 16 clinical trials
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