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Breast Gastrointestinal Genitourinary Gynecologic Hematology Lung Melanoma Solid Tumor

Phase

III II I

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Antibody-drug conjugate (RG6109) Antibody-drug conjugate (RG6148) Anti-MUC16 TDC (RG7882) Anti-TIGIT MAb (MTIG7192A, RG6058) Atezolizumab (anti-PDL1 MAb) (RG7446) BET inhibitor (TEN-010, RG6146) Bevacizumab (anti-VEGF Mab) CD20 TCB (RG6026) CD20 TDB (RG7828) CEA TCB (RG7802) Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) ChK1 inhibitor (GDC-0575, RG7741) Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) Codrituzumab (anti–glypican-3 MAb) (GC33, RG7686) Emactuzumab (anti–CSF-1R MAb) (RG7155) Entrectinib FAP-DR5 biMAb (RG7386) FAP-IL2v FP (RG7461) Glypican-3/CD3 biMAb (CHU) Idasanutlin (MDM2 antagonist) (RG7388) Ipatasertib (Akt inhibitor) (GDC-0068, RG7440) Monoclonal antibody (RG6160) Monoclonal antibody (RG6194) Obinutuzumab Pan-RAF inhibitor (RG6185) Personalized cancer vaccine (RG6180) PI3K inhibitor (GDC-0077, RG6114) Polatuzumab vedotin (anti-CD79b ADC) (RG7596) Raf/MEK dual inhibitor Selective estrogen receptor degrader (SERD[3]) (GDC-9545, RG6171) Selicrelumab (anti-CD40 MAb) (RG7876) Taselisib (PI3K inhibitor) (GDC-0032, RG7604) Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601)

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Tumor Type: Solid Tumor

Phase: PHASE I

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Molecule:

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Tumor Type Phase Molecule* Location Study Contact
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) AR NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) AR
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) AZ NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) AZ
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) CA NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) CA
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) CA NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) CA
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) DE NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) DE
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) ES NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) ES
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) FL NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) FL
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) FR NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) FR
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) GB NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) GB
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) IL NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) IL
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) IT NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) IT
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) MA NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) MA
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) NY NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) NY
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) PA NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) PA
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) TX NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Solid Tumor II, I Cobimetinib (MEK inhibitor) (GDC-0973, RG7421) TX
NCT02639546—Safety and Pharmacokinetics of Cobimetinib in Pediatric and Young Adult Participants With Previously Treated Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) AR NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) AR
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) AU NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) AU
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) CA NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) CA
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) CA NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) CA
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) CT NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) CT
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) ES NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) ES
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) FR NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) FR
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) KR NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) KR
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) MA NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) MA
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) MD NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) MD
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) NY NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) NY
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) TN NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Solid Tumor I Anti-TIGIT MAb (MTIG7192A, RG6058), Atezolizumab (anti-PDL1 MAb) (RG7446) TN
NCT02794571—Safety and Pharmacokinetics (PK) of Escalating Doses of MTIG7192A as a Single Agent and in Combination With Atezolizumab in Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel CO NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel CO
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel CT NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel CT
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel DC NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel DC
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel JP NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel JP
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel KR NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel KR
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel MA NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel MA
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel MN NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel MN
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel NC NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel NC
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel NY NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel NY
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel TN NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel TN
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel TW NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel TW
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel WI NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Bevacizumab (anti-VEGF Mab), Capecitabine, Paclitaxel WI
NCT02715531—A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) CA NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) CA
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) CH NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) CH
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) CT NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) CT
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) DK NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) DK
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) ES NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) ES
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) NL NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) NL
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) NY NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) NY
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) TN NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Cergutuzumab amunaleukin (CEA-IL2v) (RG7813) TN
NCT02350673—A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) CT NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) CT
NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) ES NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) ES
NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) FR NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) FR
NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) MA NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) MA
NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) NY NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Emactuzumab (anti–CSF-1R MAb) (RG7155) NY
NCT02323191—A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) AZ NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) AZ
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CA NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CA
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CA NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CA
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CO NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CO
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CT NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) CT
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) GB NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) GB
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) NV NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) NV
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) NY NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) NY
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) OR NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) OR
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) TN NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Personalized cancer vaccine (RG6180) TN
NCT03289962—A Study of RO7198457 (Personalized Cancer Vaccine [PCV]) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) AL NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) AL
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) AZ NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) AZ
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) CA NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) CA
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) DK NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) DK
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) ES NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) ES
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) FR NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) FR
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) NL NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Selicrelumab (anti-CD40 MAb) (RG7876) NL
NCT02304393—A Study of RO7009789 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) BE NCT01688206—A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) BE
NCT01688206—A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) ES NCT01688206—A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) ES
NCT01688206—A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) FR NCT01688206—A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Solid Tumor I Atezolizumab (anti-PDL1 MAb) (RG7446), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) FR
NCT01688206—A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) CA NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) CA
NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) DK NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) DK
NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) ES NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) ES
NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) NL NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Solid Tumor I Bevacizumab (anti-VEGF Mab), Selicrelumab (anti-CD40 MAb) (RG7876), Vanucizumab (anti–ANG2-VEGF biMAb) (RG7221) NL
NCT02665416—Study Evaluating the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Therapeutic Activity of RO7009789 With Vanucizumab or Bevacizumab in Participants With Metastatic Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib CA NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib CA
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib CO NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib CO
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib GA NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib GA
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib IL NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib IL
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib MA NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib MA
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib MN NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib MN
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib MO NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib MO
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib NY NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib NY
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib OH NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib OH
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib OR NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib OR
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib PA NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib PA
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib TN NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib TN
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib TN NCT03330990—Evaluate the Effect of Entrectinib on the Pharmacokinetics of Midazolam in Cancer Patients
Solid Tumor I Entrectinib TN
NCT03330990—Evaluate the Effect of Entrectinib on the Pharmacokinetics of Midazolam in Cancer Patients
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib TX NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib TX
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Entrectinib UT NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Solid Tumor I Entrectinib UT
NCT02650401—Study of RXDX-101 in Children With Recurrent or Refractory Solid Tumors and Primary CNS Tumors, With or Without TRK, ROS1, or ALK Fusions
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) CO NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) CO
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) CT NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) CT
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) MO NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) MO
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) NV NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) NV
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) OK NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) OK
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) TN NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) TN
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) TX NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) TX
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) VA NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Solid Tumor I Idasanutlin (MDM2 antagonist) (RG7388) VA
NCT03362723—A Study to Investigate the Bioequivalence or Relative Bioavailability of Three New Idasanutlin Tablet Variants Following Oral Administration in Participants With Solid Tumors
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) CA NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) CA
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) ES NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) ES
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) FR NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) FR
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) GB NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) GB
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) MA NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) MA
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) NY NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) NY
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) TN NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Solid Tumor I PI3K inhibitor (GDC-0077, RG6114) TN
NCT03006172—To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab AZ NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab AZ
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab CA NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab CA
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab CO NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab CO
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab DK NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab DK
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab ES NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab ES
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab FR NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab FR
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab GB NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab GB
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab IT NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab IT
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab NL NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab NL
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I RO6874281, Trastuzumab NY NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Solid Tumor I RO6874281, Trastuzumab NY
NCT02627274—A Study Evaluating Safety, Pharmacokinetics, and Therapeutic Activity of RO6874281 as a Single Agent (Part A) or in Combination With Trastuzumab or Cetuximab (Part B or C)
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) AZ NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) AZ
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) CA NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) CA
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) CA NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) CA
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) ES NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) ES
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) FL NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) FL
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) IL NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) IL
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) MA NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) MA
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) MO NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) MO
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) NY NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) NY
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) OK NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) OK
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) TN NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) TN
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) TX NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Solid Tumor I Taselisib (PI3K inhibitor) (GDC-0032, RG7604) TX
NCT01296555—A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma (NHL) and in Combination With Endocrine Therapy in Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) AU NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) AU
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) CA NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) CA
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) CH NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) CH
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) CO NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) CO
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) MA NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) MA
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) NL NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) NL
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) TN NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) TN
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Tumor
Type
Phase Molecule* Location
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) WA NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Solid Tumor I Venetoclax (BCL-2 inhibitor) (ABT-199/GDC-0199, RG7601) WA
NCT03236857—A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
1 of 136 clinical trials
1-4 of 136 clinical trials
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